Vaccinations could be made less painful by treating skin with a vaccine-laden liquid and using ultrasound to push it into the body

Vaccines can be delivered through the skin using ultrasound. This method doesn’t damage the skin and eliminates the need for painful needles. To create a needle-free vaccine, Darcy Dunn-Lawless at the University of Oxford and his colleagues mixed vaccine molecules with tiny, cup-shaped proteins. They then applied liquid mixture to the skin of mice and exposed it to ultrasound – like that used for sonograms – for about a minute and a half.

  • abraxas@sh.itjust.worksEnglish
    2·
    11 months ago

    Yeah. I half-mentioned it elsewhere. I was in an ER and needed to have blood drawn. I was just barely staying conscious by leaning back with an ice pack, but they needed the room so a nurse came in and said “yeah you’re fine” and lugged me from the blood-draw chair into a wheelchair. My wife wanted to hit her (lol) but it took the 2 of them to keep me from hitting the floor instead of the wheelchair because I started to black out from suddenly standing.

    Some nurses are idiots.

    • PsychedSy@sh.itjust.worksEnglish
      1·
      11 months ago

      Jesus. I had a nurse accidentally throw a vial (one of like 11. It was my first RA blood draw) in the biohazard bin. She took one look at me and ripped that box off the wall to carefully extract it, risking herself in the process.

      Recently they moved half the infusion staff to another location and a nurse I’d never met, who’s a super nice guy, just isn’t as careful when he’s finishing up as the women have been. First bruise I’ve gotten from them in like two years. My arm looked like I was shooting up heroin or something. No real damage, but it’s unsettling.

      • abraxas@sh.itjust.worksEnglish
        2·
        11 months ago

        Yeah, exactly. And I agree that there’s separate categories for skill, dedication, and niceness. Some folks are damn good but lazy and don’t care, others make up for being “only ok” by trying really hard and caring a lot, and some are just friendly when they screw up. It’s nice to have more than 1 of those 3 at a time. Someone in my family went to a weight loss doctor and asked me to come along. She was the friendliest doctor I’d ever seen… and the appointment finished with “I’m really lost. I don’t think there’s anything else we can try right now. You’re doing everything right”. Don’t know WHAT that was in the spectrum of skill and dedication. Maybe it’s true, maybe she was just giving up. But from what I’ve seen/heard, it’s definitely better than “well try harder, eat less, and workout more” that heavier patients hear from doctors who don’t even ask what they’re eating or what their workout regimen looks like.

        I don’t have to deal with a lot of that stuff you do, but I can imagine it since what little I deal with has shown me multiple sides of people (doctors too, I suppose).

        • PsychedSy@sh.itjust.worksEnglish
          1·
          11 months ago

          My worst was my GP/PCP saying all men are a little ADHD. I got an official diagnosis with ease. Now I use a doctor recommended by a friend and she’s fantastic. All my docs are women now, and I only use men for mental health stuff. It’s worth it hunting down the right people if you can. I’m kinda lucky with my insurance. I use a badass local pharmacy, too, and their competence is mind blowing compared to big corporate pharmacies.

          What fucked me up with the nurse was that the first time I met him he just finished the infusion. Took the tape off and pretty much dropped the IV rig. It just bruised a bit, but was distressing to watch. The second time I saw him I was like “oh fuck oh shit” but he had no problems. Got it on the first attempt. Painless. He’s just way too chill on the back end.